the treatment of mixed infections with roundworms and flatworms (roundworms and
tapeworms) in cats. Since a tapeworm infestation may not occur in the cat,
right up to the third week of life, treatment with Drontal is not indicated
until after the third week of life of the animal.
AND QUANTITATIVE COMPOSITION
tablet contains: Active Substances: Pyrantel Emollate 230.0 mg Praziquantel
medicinal product is an anthelmintic intended to combat nematodes and cestodes
containing active substances the praziquantel (a derivative of the
pyrazinoisoquinolone) and the derivative of tetrahydropyrimidine pyrante (as
the encasing salt).
this fixed combination praziquantel acts against the cestodes and its spectrum
of action covers all relevant cat species of the cat, namely species of Taenia,
Joyeuxiella spp., Dipylidium caninum, Mesocestoides spp., Echinococcus
granulosus and Echinococcus multilocularis. Praziquantel acts against all
stages of these parasites at cat's gut level.
is absorbed, very rapidly, through the surface of the parasite, distributing
uniform manner therein. The occurrence of severe lesions at the integument of
the parasite is very rapid, both in vitro and in vivo, resulting in contraction
and paralysis of the parasites. The base for the rapid triggering of action
lies, above all, in the praziquantel-induced of the membrane permeability of
the parasite to Ca ++, which results in metabolic dysregulation of the
is the specific component against nematodes and shows good efficacy against all
relevant cat nematodes, in particular Toxocara cati (syn. mystax), Toxascaris
leonina and Ancylostoma spp. Pyrantel acts as a cholinergic agonist with
nicotine-like action and causes spastic paralysis of the nematodes through a
depolarizing neuromuscular block.
of administration: oral. The recommended dose is a single administration of 5
mg praziquantel and 57.5 mg pirantel embenus per kg body weight (equivalent to
1 tablet per 4 kg body weight).
tablets may be administered directly or mixed with food. No dietary measures